What is the LD50 of caffeine?
The LD50 of caffeine in humans is dependent on individual sensitivity, but is estimated to be 150–200 milligrams per kilogram (2.2 lb) of body mass (75–100 cups of coffee for a 70 kg (150 lb) adult). There are cases where doses as low as 57 milligrams per kilogram have been fatal.
What is LD50 quizlet?
A commonly used measure of toxicity is the LD50. = the lethal dose in milligrams of chemical per kilogram of body weight (mg/kg) for 50% of a test population.
What is the significance of a low LD50?
A low LD50 means the species is highly susceptible to the poison. The LD50 for a particular poison can vary greatly between different species of animals. Since LD50 is quoted in mg/kg of body weight, the amount of poison to kill an animal is a direct function of the species’ body weight.
What is the LD50 of arsenic?
Arsenic. Elemental arsenic has an LD50 of around 13 mg/kg – orders of magnitude higher than some of the substances on this list.
What is the most toxic substance in the universe?
How long does thallium stay in your body?
Most of the thallium leaves your body in urine and to a lesser extent in feces. It can be found in urine within 1 hour after exposure. After 24 hours, increasing amounts are found in feces. It can be found in urine as long as 2 months after exposure.
Does thallium affect the kidneys?
Thallium compounds can affect the respiratory, cardiovascular, and gastrointestinal systems, liver, kidneys, and the male reproductive system. Temporary hair loss has also been associated with ingestion of thallium in humans.
Why is it so difficult to get thallium out of the body?
Many thallium(I) compounds are highly soluble in water and are readily absorbed through the skin. Exposure to them should not exceed 0.1 mg per m2 of skin in an 8 hour time-weighted average (40 hour work-week). Thallium is a suspected human carcinogen….